The effect of white matter hyperintensities on regional brain volumes and white matter microstructure, a population-based study in HUNT
نویسندگان
چکیده
منابع مشابه
Regional variation models of white matter microstructure
Diffusion-weighted MRI (DW-MRI) is a powerful in vivo imaging technique that is particularly sensitive to the underlying microstructure of white matter tissue in the brain. Many models of the DW-MRI signal exist that allow us to relate the signals we measure to various aspects of the tissue structure, including measures of diffusivity, cellularity and even axon size. From histology, we know tha...
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White matter hyperintensities (WMH) of presumed vascular origin are a common finding in brain magnetic resonance imaging of older individuals and contribute to cognitive and functional decline. It is unknown how WMH form, although white matter degeneration is characterized pathologically by demyelination, axonal loss, and rarefaction, often attributed to ischemia. Changes within normal-appearin...
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Case-control studies showed that migraine is associated with ischemic stroke. Studies assessing the prevalence of white matter lesions (WML) in migraine however, reported conflicting results, possibly attributable to selection bias by recruiting only severe cases. We conducted a population-based MRI study of migraineurs with aura (N=161), migraineurs without aura (N=134) and controls (N=140), 3...
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The severity of tissue changes associated with incidental white matter hyperintensities (WMH) in the elderly cannot be sufficiently determined by conventional MRI. We, therefore, performed a regional analysis of the magnetization transfer ratio (MTR) maps obtained on a 1.5 T scanner from 198 neurologically asymptomatic participants of the Austrian Stroke Prevention Study (mean age 70, age range...
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OBJECTIVE To evaluate the brain status of patients with systemic sclerosis (SSc). METHODS Fourteen female patients with SSc aged 24-74, with a disease duration of 1-12 years and without other relevant systemic diseases, were enrolled. All patients and an age matched female control group (CG) of 14 clinically normal subjects, underwent brain magnetic resonance examination at 1.5 T; spin echo p...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2019
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2019.116158